Aziz Ansari and Amy Schumer

Anthony reveals the best part of being pope, explores the funny side of cancer, and asks an expert about d**k pics.

Nick Kroll and Patton Oswalt

Anthony shares some child mortality stats, explores what happens when group sex gets violent, and makes Patton and Nick defend their tweets.

Billy Eichner and Kristen Schaal

Anthony finds the funny side of child abduction, shames the elderly and investigates Obama's sexuality.

Doug Benson and Brian Posehn

Anthony defends Justin Bieber, chats about baby AIDS and uncovers the lighter side of necrophilia.

Brett Gelman and Andy Kindler

Anthony shows off his staff's diversity, discovers strip club tax breaks, and makes Andy and Brett defend their tweets.

Jonah Ray and Jeff Ross

Jeff and Jonah defend their tweets, discuss whether Barack Obama is Satan, and review Casey Anthony's parenting skills.

T.J. Miller and John Mulaney

The Colorado shooter converts to Islam, bullet wounds look just like Italian food up close, and Anthony makes John and T.J. defend their tweets.

Natasha Leggero and Jason Mantzoukas

A California chef slow-roasts his wife, two teens try to poison their teacher, and Jason and Natasha defend their tweets.

Abby Elliott and Pete Holmes

Indian scientists design lingerie that shocks potential rapists, a Georgia high school has its first integrated prom in 30 years, and Pete and Abby defend their tweets.

Kumail Nanjiani and Reggie Watts

Justin Bieber makes a Holocaust gaffe, a suspected murderer gets into the art business, and Kumail and Reggie defend their tweets.

Amy Schumer & Jim Norton

Anthony learns the ins and outs of necrophilia, we learn the history of the great Panel, football player Aaron Hernandez covers his murderous tracks, and Amy & Jim defend their tweets.

Kumail Nanjiani & David Koechner

Anthony explores satanism, David Koechner has it out for Ariel Castro, and we explore Craigslist.

Adam Pally & Casey Wilson

Doug Benson & Rob Huebel

Batman and Superman are teaming up, we're facing a nationwide sperm shortage, and chats with some experts about drunk driving.

Joan Rivers & Dave Attell

Anthony goes after Islam, Joan Rivers explains why Old Sex is the best, and Dave Attell finds his inner Latino.

Eric André & T.J. Miller

Anthony critiques celebrity fashion, TJ Miller gets under Anthony's skin, and Eric André has plenty of surprises of his own.

Thomas Lennon & Marc Maron

Anthony is joined by Thomas Lennon and Marc Maron, and takes a look at body dysmorphia and plastic surgery in the segment "Sacred Cow."

Nick Kroll & John Mulaney

Anthony is joined by Nick Kroll and John Mulaney, and plays thegame "How Many Things?"